It continues to be an exciting time for BlueRock Therapeutics as the company advances cutting edge cellular therapies to positively impact patients’ lives across multiple disease areas.
The Senior Manager (Ophthalmology), Translational Medicine, will be expected to take on a highly visible role with internal and external stakeholders through the management of the imaging protocols leveraged in BlueRock’s clinical development programs. The Senior Manager will leverage their expertise in ophthalmic imaging to advance the company’s development pipeline by working closely with the Translational Medicine leaders and other subject matter experts. As part of the Translational Medicine team, this role also provides unique exposure into non-imaging biomarkers. The position will be based in Cambridge, Massachusetts
Responsibilities:
- As a critical member of the Translational Medicine team, the Senior Manager of Imaging will leverage their expertise in ophthalmic, and ideally also CNS, imaging to:
- Act as an internal clinical imaging expert in OCT, FAF, and FA techniques.
- Partner with the Translational Leads and Clinical Development teams to lead the use of clinical imaging endpoints across all phases of drug development.
- Propose and execute imaging biomarker validation studies to enable the use of imaging endpoints as decision-making.
- Oversee CRO vendor/partners ensuring that they optimally execute clinical and preclinical imaging projects in the US, Europe and other geographies as needed.
- Ensure timely execution of imaging trials, including providing adequate operational support.
- Collaborate with the Research teams to lead preclinical imaging studies and ensure translational relevance of selected readouts.
- Provide support to the Business Development organization on diligence efforts.
Minimum Requirements:
- Ph.D. in an imaging related discipline with at least 3+ years of industry experience and recognition as a contributor in the field of preclinical and clinical imaging science.
- Ophthalmology imaging experience required.
- Must have direct experience managing imaging protocols in the conduct of clinical trials (endpoints, inter-site harmonization, imaging core lab oversight, etc.).
- Specific experience with imaging endpoints as decision-making in ophthalmic disease required.
- Subject matter expertise in MRI, PET, and SPECT preferred.
Working Environment:
- Full time
- Remote or hybrid can be arranged
